Dr Giulia Nadasan. Vet Point Vest. Arad,Romania. Patient: Ellie. Species: canine. Breed: mix German Shepherd. Age: 9 years. Anamnesis: the. Request PDF on ResearchGate | On Feb 1, , Abouali F and others published Intoxication aux raticides. Download Citation on ResearchGate | Intoxication volontaire aux raticides chez une adolescente | Suicide attempts are frequent during adolescence. Intentional .

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Numerous other brand products containing either 0. After too weeks our suspected diagnosis was confirmed: Presence of specific abnormalities on electroencephalogram and a positive Fujiwara-Ross reaction in an urine sample are additional elements for the diagnosis. Some rodenticides are lethal after one exposure while others require more than one.

The prognosis is usually good after early management which combines gastric lavage, activated charcoal, sedation with benzodiazepines, tracheal intubation and artificial ventilation if required. The therapy with commercially available calcitonin preparations is, however, expensive. Integrated Pest Management Index of pesticide articles Pesticide categories.

Before the advent of anticoagulants, phosphides were the favored kind of rat poison. In addition to this specific metabolic disruption, massive toxic doses of 4-hydroxycoumarin4-thiochromenone and indandione anticoagulants cause damage to tiny blood vessels capillariesincreasing their permeability, causing internal bleeding.

Contact Help Who are we? These preparations rely on dehydration to cause death. For the window manager, see ratpoison.

Intoxication with anticoagulant raticides

We performed and ultrasound and there was free fluid in the abdomen and after the paracentesis we removed aprox. Pages containing links to subscription-only content Use dmy dates from January All articles with unsourced statements Articles with unsourced statements from November From Wikipedia, the free encyclopedia.

La reprise de l’interrogatoire des parents et le tableau clinique ont permis de confirmer une intoxication intozication un raticide contenant du chloralose. Signs generally raticifes within hours of ingestion and can include depression, anorexia, polyuria and polydipsia.

The aim of this association is that the antibiotic suppresses intestinal symbiotic microflorawhich are a source of vitamin K.


A second parental interview and clinical presentation confirmed an intoxication with a rodenticide containing alpha-chloralose. PoisoningRodenticides, Infant.

Rodenticide – Wikipedia

A bait consisting of food and a phosphide usually zinc phosphide is left where the rodents can eat it. Access to the text HTML. These effects are gradual, intoxicahion over several days. The late clinical orientation did not allow us to perform a urinanalysis.

Splenomegaly with ruptured spleen was our main concern, we did a splenectomy and removed aprox 4L of free blood from the abdomen. Besides being directly toxic to the mammals that ingest them, including dogs, cats, and humans, many rodenticides present a secondary poisoning risk to animals that hunt or scavenge the dead corpses of rats.

Anticoagulants are defined as chronic death occurs one to two weeks after ingestion of the lethal dose, rarely soonersingle-dose second generation or multiple-dose first generation rodenticides, acting by effective blocking of the vitamin K cycle, resulting in inability to produce essential blood-clotting factors—mainly coagulation factors II prothrombin and VII proconvertin.

Environmental Ratucides Agencyexamples of first generation agents include chlorophacinone and diphacinone. Retrieved 22 August This has led environmental researchers to conclude that low strength, long duration rodenticides generally first generation anticoagulants are the best balance between maximum effect and minimum risk. Upon single ingestion, solely calciferol-based baits are considered generally safer to birds than second generation anticoagulants or acute toxicants.

Rodenticidescolloquially rat poisonare typically non-specific pest control chemicals made and sold for the purpose of killing rodents.

In other projects Wikimedia Commons. We report a case of an accidental intoxication in a month-old boy resulting from the ingestion of a rodenticide containing alpha-chloralose. Campbell Island conservation sanctuary rat free”.


Marcoux bE. The odor attracts or, at least, does not repel rodents, but has an repulsive effect on other mammals. Parental interview revealed he had episodes of shaking in the afternoon.

Cheuret cK. Severe clinical cases described in voluntary intoxications in adults and teenagers occur very rarely in toddlers. The acid in the digestive system of the rodent reacts with the phosphide to generate the toxic phosphine gas. Alberta, Canadathrough a combination of climate and control, is believed to be rat-free. According to some sources, the indandiones are considered second generation. Inversely, the individual rodents, that survived anticoagulant bait poisoning rest population can be eradicated by pre-baiting them with nontoxic bait for a week or two this is important to overcome bait shyness, and to get rodents used to feeding in specific areas by specific food, especially in eradicating rats and subsequently applying poisoned bait of the same sort as used for pre-baiting until all consumption of the bait ceases usually within 2—4 days.


Some of these poisons act by inhibiting liver functions and in advanced stages of poisoning, several blood-clotting factors are absent, and the volume of circulating blood is diminished, so that a blood transfusion optionally with the clotting factors present can save a person who has been poisoned, an advantage over some older poisons.

A specific antidote for calciferol intoxication is calcitonina hormone that lowers the blood levels of calcium. Zinc phosphide is typically added to rodent baits in a concentration of 0.

GI smooth muscle excitability decreases and is manifest by anorexia, vomiting and constipation. Diminished production of vitamin K by the intestinal microflora contributes to the action of anticoagulants.

Median intxoication time with spelectomy and doxorubicine is days. It is considered to be single-dose, cumulative depending on concentration used; the common 0. Vitamin K 1 has been suggested, and successfully used, as antidote for pets or humans accidentally or intentionally exposed to anticoagulant poisons. In the final phase of the intoxication, the exhausted rodent collapses due to hemorrhagic shock or severe anemia and dies calmly.

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