Hereditary gingival fibromatosis (HGF), also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth. HGF is characterized as a . Hereditary, drug-induced, and idiopathic gingival overgrowth have been reported . Hereditary gingival fibromatosis can occur as an isolated. Mutation in SOS1, son-of-sevenless gene, is thought to be responsible for hereditary gingival fibromatosis. This report shows a case of.

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Idiopathic gingival fibromatosis case report.

If the patient’s disease is treated by means of surgery, it is recommended that the patient undergoes post-surgical therapies for maintenance and periodic monitoring of gums for the sake of the possibility of re-occurrence of HGF. J Am Dent Assoc. A preliminary communication with special reference to hereditary generalized gingival fibromatosis.

Intraoral examination showed yereditary development of the dentition. Treatment is not required in all cases of idiopathic gingival hyperplasia.

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Hereditary gingival fibromatosis: Characteristics and treatment approach

This case study also acknowledged how HGF can be part of a multi-system syndrome associated with disorders such as Zimmermann Laband syndrome ear, nose, bone, and nail defects with hepatosplenomegalyRutherford syndrome microphthalmia, mental retardation, athetosis, and hypopigmentationMurray-Puretic Drescher syndrome and Ramon syndrome.

Familial gingival fibromatosis associated with progressive deafness in five generations of a family. Intraoral view of maxillary arch showing a gross generalized growth of gingiva completely covering the maxillary teeth extending from right maxillary tuberosity to left tuberosity region.


Clinical examination showed persistence of the primary incisors, no eruption of the permanent incisors and lack heredltary lip closure.

Hereditary Gingival Fibromatosis: A Review and a Report of a Rare Case

It covers the teeth partially or totally and can be localized or generalized, with a variable degree of severity, but does not affect the bone 2458 Lateral cephalogram showing mandibular deficiency and vertical growth pattern. The extent and severity of fibromatosis in this case has covered almost all teeth thereby causing difficulty in mastication and speech. There was significant blood loss during the surgery which was compensated by putting the patient on blood transfusion 2 pints of ml each over 2 days.

Panoramic radiograph showing multiple retained primary and impacted permanent teeth. In some cases it shows only minimal involvement characterized by enlargement of the tuberosity area and buccal gingiva around the mandibular molars; however, in severe form it can involve both maxillary and mandibular gingiva.

Hereditary gingival fibromatosis: Characteristics and treatment approach

The growth was pink to pinkish white in color. Post surgically her facial profile improved dramatically and the patient was satisfied with the result [ Figure 3 ].

Fibrous hyperplasia of the gingival; pp. Source 1 Later on inthere was a case study done on a year-old male with severe gingival overgrowth, almost covering all teeth. HGF generally has two forms based on the extent of involved tissue, including nodular localized, mostly seen in the maxillary tuberosity and molar area and symmetric generalized, which is more common and both arches are equally affected forms [ 13 ].


A family pedigree of four generations. The patient noted the growth 3 years back, since then it was progressively increasing in size causing inadequate lip apposition and poor esthetic.

A cold scalpel provides greater tactile sensitivity and is preferable to laser: At the time they visited a general dental practitioner who suggested quadrant wise gingivectomy. J Clin Periodontol HGF may also be caused by unwanted side effects of pharmacological agents like phenytoinciclosporinand some calcium-channel blockers, meaning HGF is a disease that can fibromatossis drug-induced. Additional information Further information on this disease Classification s 2 Gene s 3 Clinical signs and symptoms Publications in PubMed Other website s 0.

Introduction Hereditary gingival fibromatosis HGF is a rare hereditagy with the prevalence of one per population and equal distribution in sexes [ 1 ]. Diffuse fibroma of gums.

Development of a classification system for periodontal diseases and conditions.

She had no history of epilepsy or mental disorder. Here, an interesting case report of massive HGF has been presented. Gingival abnormalities of genetic origin: Gingival overgrowth in children: There were no fluctuancy, no compressibility, no translucency, and no associated bleeding noted.